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HaCaT keratinocytes have also been proven to be good candidates for assessing skin irritancy and toxicity in conventional monolayer assays measuring using MTT reduction as the viability endpoint 21

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1 2 "We propose that the parallel evolution observed at this site is an adaptive response to an environmental toxin and that sequencing of historical alleles suggests that this toxin was not a synthetic insecticide." 1 2 "The lines from Kazakhstan, Sweden, Ukraine, and 1 of the United States lines were collected before 1940 and hence represent pre-DDT lines." 1 2 "From the sequence data all D