Furthermore, NAC normalized the altered GSH levels displayed by these animals in the hippocampus and nucleus accumbens, and it partially rescued the altered expression of post-synaptic terminal network genes found in VPA-exposed rats, such as NR2a, MGLUR5, GLUR1 , and GLUR2 in nucleus accumbens, and CAMK2, NR1 , and GLUR2 in cerebellum
Genetic evidence for the role of uric acid in Parkinsons disease While, as mentioned, UA derives from the metabolism of purine and hence will be influenced by diet, serum UA is primarily related to genetic factors, particularly those associated with UA transport
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