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doi: 10.1073/pnas.1803406115 34 DongK.ZhuY.DengQ.SunL.YangS.HuangK.et al

It inhibits melanin formation: It functions by inhibiting tyrosinase, an enzyme, which as a result causes inhibition of melanin a pigment that causes dark pigmentation and an uneven skin tone

Strauss, K

For example, when hist amine is released during an allergic response, binding to the H1 receptor results in cell signaling that stimulates mucus secretion, increases vasodilation and vascular permeability and can lead to bronchoconstriction in allergy-induced asthma