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While more human trials are needed to further explore this topic, one study showed depleted levels of glutathione in the hippocampus of generally healthy elderly persons, resulting in mild cognitive impairment, a precursor to more advanced impairment down the road

Neurons located in the ventral subparaventricular zone of the hypothalamus, which send projections to the dorsomedial hypothalamus, are also essential for the circadian sleep-wake cycle

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