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Description A peptidase labile sequence that links drugs to proteins or lipophilic carriers

Int J Cancer 127:18131822 Souers AJ, Leverson JD, Boghaert ER, Ackler SL, Catron ND, Chen J, Dayton BD, Ding H, Enschede SH et al (2013) ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets

In another study, the specificity of the HPRP-A1 peptide compared with the HPRP-A1-TAT peptide was evaluated

Furthermore, treatments that target the interaction between PNPLA3 and ABHD5 (70) or the degradation of PNPLA3 (74) could be of therapeutic benefit to patients that carry the PNPLA3 I148M variant