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Folate and nucleic acid metabolism The figure highlights that riboflavin in the form of flavin adenine dinucleotide (FAD) is a required cofactor for the enzyme methylenetetrahydrofolate reductase (MTHFR), which reduces 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate

[DOI] [PubMed] [Google Scholar] 90.Kuemmerle-Deschner JB, Haug I

Untreated vitamin B12 deficiencies can lead to neurological issues or pernicious anemia which can occur when your body does not have enough vitamin B12 to produce the amount of red blood cells it needs