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This mechanism is based on interaction with receptors in the brain, leading to the synchronization of brain waves

Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides

However, the fact that the turnover numbers are quite low and similar to those obtained with other oxidoreductases (Grxs, Trxs, GSTOs, GHRs, and DHARs) from various organisms (Lallement et al., 2014) and that a quercetin derivative was also isolated from a ligand fishing experiment performed with a Phi GST (Dixon et al., 2011) raises the question of a specific role of GSTLs in quercetin recycling and in the maintenance of a reduced flavonoids pool