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PTX3 can increase the expression of endothelial tissue factors and participate in the formation of thrombosis and vascular ischemia of tissue factors by endothelial cells (Napoleone et al., 2002)

One regulatory note worth holding alongside his framing: the FDA placed several of the peptides he discusses (including BPC-157, CJC-1295, and Ipamorelin) onto a Category 2 list in 2023, citing a lack of safety data rather than reported harms

Current British Society of Gastroenterology guidance suggests considering a baseline upper GI endoscopy with biopsies in adults aged 50 or over with confirmed pernicious anaemia to document autoimmune gastritis

Faseb J 2002