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MRS data analysis We applied a weighted combination of receiver channels, followed by motion corruption average removal, spectrum registration for frequency and phase drift correction, and pre-subtraction sub-spectral alignment in MATLAB 2019a (The Mathworks, Natick, MA, USA) using the FID-A toolkit before signal averaging and data analysis 56

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Hum Exp Toxicol 41:09603271221111333 Cao Y, Xu Z, Chen Y, Jiang S, Li H, Luo Y (2016) Effects of Dioscorea nipponica on the expression of Th17/Treg cytokines in patients with Hashimoto thyroiditis