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Macrophages can derive from embryonic hematopoietic precursors and inhabit specific tissues, in which they actively participate in maintaining homeostasis under physiological conditions

Furthermore, alcohol and certain medications such as phenobarbital, phenytoin (Dilantin), carbamazepine (Tegretol) (anti-seizure medications), or isoniazid (INH, Nydrazid, Laniazid) - (anti-tuberculosis drug) can significantly increase the damage

Zu bemerken ist, dass diese Patienten aufgrund ihrer Grundkrankheit oder der Vortherapie bereits Risikopatienten sind

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