Next, a specialized transport antiporter protein called Carnitine-Acylcarnitine Translocase (CACT) ferries this acylcarnitine complex across the impermeable inner membrane and deep into the mitochondrial matrix, while simultaneously pumping a free L-carnitine molecule back out to maintain the cycle
Concurrently, hyperphosphorylation and its abnormal accumulation, coupled with impaired clearance, lead to the formation of NFTs, further compromising neuronal function
(1941): A method for determining loss of pain sensation
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