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Ferroptosis has recently been identified as a regulated mode of cell death, and a growing number of studies have demonstrated that ferroptosis is closely related to the occurrence and development of various CVDs

Healthspans topical rapamycin isnt a cosmetic quick fixits a clinician-developed treatment that targets three critical drivers of skin aging: reducing the buildup of senescent cells, lowering inflammation in the skin layer, and boosting collagen production

This occurs through the action of mobilized FAs that function as allosteric activators of uncoupling protein 1 (UCP1), the molecular mechanism for heat generation in brown fat (6, 100)

These findings suggest significant metabolic modulation potential for further investigation