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Therefore, we used the more conservative estimate of a 20% reduction for our sample size, resulting in as minimum of 41 subjects for our study

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Griesbach and colleagues (2004) showed that exercise initiated immediately after a mild fluid percussion injury decreases synaptic plasticity molecules (including phosphorylated CREB [cAMP response element-binding protein], synapsin I, and mitogen activated protein kinase) and worsens spatial learning and memory tasks in the adult rat