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ATF4 transcription plays a key role in maintaining cellular homeostasis, thereby promoting cellular adaptation

Relations between chemical structure and biological activity in peptides

As the glutamate-induced swelling is sensitive to the specific K + channel blockers, namely Ba 2+ and tetraethylammonium (TEA), it is likely that delayed outwardly and inwardly rectifying K + channels are involved (Bender et al., Regulatory Volume Decrease (RVD) As uncontrolled volume changes are harmful to cells and may eventually lead to cell death, mechanisms controlling the cell volume are essential for physiological cell functioning

Journal of Biomaterials Science, Polymer Edition, 20(12):15371552