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FOXO4-DRI is a D-retro-inverso peptide, meaning its amino acid sequence is reversed and uses mirror-image D-amino acids, making it resistant to enzymatic degradation while maintaining binding activity

These microscopic carriers protect glutathione as it passes through the digestive tract, allowing significantly higher absorption

These approaches aim to enhance treatment efficacy while reducing damage to the normal hematopoietic system, either by selectively inducing LSC clearance or remodeling the bone marrow immune microenvironment

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