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We propose a highly promising strategy: by employing imaging modalities such as positron emission tomography (PET) or optical imaging, this approach allows for real-time, spatial mapping of ICD occurrence, revealing both the specific regions and the extent of immunogenic cell death within tumor tissues

For adenovirus infection, PDX cells or NHAs were infected with indicated adenoviruses at a multiplicity of infection (MOI) of 30 and replaced with fresh DMEM 6 h after viral infection

Injection of the autophagy inducer Tat-Beclin-1 increases mitophagy, reducing mitochondrial dysfunction, cardiomyocyte hypertrophy, and heart failure induced by pressure overload [73]

Whether any of this translates to cancer-preventive or anti-metastatic effects in living organisms is unknown, and cancer biology is far too complex for cell culture gene expression changes to predict clinical outcomes