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We also assess the potential mechanisms that contribute to the reduction in major adverse cardiovascular events in individuals treated with GLP1R agonists and highlight the emerging cardiovascular biology of novel GLP1-based multi-agonists currently in development

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The primary mechanism of RBF autoregulation is the myogenic response of afferent arterioles and tubuloglomerular feedback, which balances afferent arteriole tone based on the amount of sodium chloride delivered to the macula densa

doi:10.1159/000014627