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The PZQ plasma exposure, measured by C max , is substantially lower than the LD 50 against adult worms and NTS reported by others 61,62 , and substantially below the LD 50 for NTS killing measured herein (2743 M)

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High-throughput UPLC-MS method for the determination of N-Acetyl-l-Cysteine: application in tissue distribution study in wistar rats