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Mortality rate of RA patients declined significantly only a few years after the introduction of anti-TNFs in clinical practice [65], while recent data suggest that patients with RA, PsA and AxSpA exhibit comparable mortality rate with the general population the past 5 years before the COVID-19 pandemic [15]

61 ECC5004 The preliminary results of the investigational agent ECC5004 phase 1 trial in non-human primates revealed a reduction in HbA1c levels, accompanied by weight loss and a decreased risk of adverse cardiovascular events, achieved through the mimicry of the hormone GLP-1

Funding Open Access funding provided by Tokyo University of Science