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aliquot and freeze at 20 C for extended storage Protect from light (wrap vial in aluminium foil or store in amber container) Label with peptide name, concentration, reconstitution date, and expiry Do not store at room temperature for extended periods (increases degradation risk) Aliquoting for Long-Term Storage Divide reconstituted solution into single-use aliquots (e.g., 100 L per tube) Freeze immediately at 20 C or 80 C Avoid repeated freeze-thaw cycles (causes peptide degradation and aggregation) Thaw each aliquot once and use immediately

Results: 19 patients (38%) reported depressive symptoms of any kind, while 31 patients (62%) showed no depressive symptoms (results are summarized in Table1)

Since Retatrutide itself requires only weekly injection, adding TB-500 minimally increases injection frequency while significantly expanding the support provided to the body