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CW, GS and CS were responsible for the study coordination, proband care and the sample collection

575 Similarly, the loss of mitochondrial complex I leads to a decrease in the ratio of NAD + /NADH and can inhibit the activity of Sirt3, thereby enhancing the protein acetylation and mPTP sensitivity

The research, led by Isaac Harris, PhD, at the Wilmot Cancer Institute, reveals that tumors may be addicted to glutathione, opening new possibilities for targeted cancer therapies