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Lamborg C

Still, the initial molecular trigger, or primum movens, remains undefined, and it is likely that no single causative mechanism can account for the clinical and molecular heterogeneity observed in ALS patients

Downregulation of SLC7A11 disrupts cysteine metabolism, leading to decreased intracellular cystine and GSH levels, impairing GPX4 activity and triggering lipid peroxide accumulation and ferroptosis (79,81,82)

In SNP-treated fruit, chlorophyll a, chlorophyll b, and total chlorophyll content decreased by 9% and 12%, 4% and 4%, and 6% and 9% on 1 d and 2 d, while they increased by 24% and 10%, 14% and 5%, and 19% and 9% on 3 d and 4 d, respectively