Evidence-based treatments for erectile dysfunction include PDE5 inhibitors (sildenafil, tadalafil, vardenafil, avanafil), lifestyle modifications, and specialist interventions
Without enough B12, people may feel tired, weak, foggy, or run-down
For weight management, NICE has appraised several licensed medicines that are available through NHS pathways or regulated private clinics: Semaglutide (Wegovy) NICE Technology Appraisal TA875 recommends semaglutide as an option for managing overweight and obesity in adults with a BMI of 35 kg/m or more (or 3034.9 kg/m in certain circumstances) alongside at least one weight-related comorbidity, when used within a specialist weight management service
However, these effects represent nutrient-correction benefits restoring adequate levels in deficient individuals rather than pharmacological enhancements beyond normal function