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Rapid acetylators were competent in isoniazid acetylation but the drug was cleared less efficiently in the slow acetylator group, which resulted in elevated serum concentration and led to adverse neurologic side effects due to an accumulation of unmetabolized drug (Brockton et al., 2000)

The estrogen-related receptor alpha (ERRalpha) functions in PPARgamma coactivator 1alpha (PGC-1alpha)-induced mitochondrial biogenesis

It is important to note that whilst NAC shows promise in laboratory and animal studies, there is no MHRA or NICE endorsement for its use specifically in treating fatty liver disease

4 capsules: 4 mL