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Braz Arch Biol Technol 56:849857

Enzymes involved in GSH biosynthesis and function like -glutamyl-cysteine ligase and glutathione synthetase are completely dependent on ATP and require magnesium as a cofactor (Bani Younes et al., 2020

Similarly, a study focusing on CLOCK-related circadian regulators in nurses, found that hypermethylation in BMAL1 gene bodies was associated with working 3 consecutive NS per week, suggesting possible epigenetic silencing affecting CLOCK transcriptional activity