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While preclinical studies offer robust evidence of the neuroprotective and anti-inflammatory properties associated with various phytochemical compounds, confirming their clinical efficacy and safety in human TBI patients is notably lacking, primarily due to the absence of comprehensive clinical data

Case reports and case series of military personnel document clinical presentation of hearing loss, disruption of vestibular function, eye irritation, symptoms of intoxication, neurological pain or discomfort, headache, dizziness and fatigue, loss of consciousness, disorientation, memory impairment, motor impairment, racing thoughts, and depression