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Specifically, the pattern of results associated with total sleep deprivation adheres to expectations, whereas the morning session conducted after 24 h of total sleep deprivation (a point where participants were reported to be most tired based on ESS scores) does not yield worse results than those obtained after 0 h, and following 8 h of recovery sleep

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There is also emerging evidence that the gut microbiome can affect tau pathology, possibly through inflammation-mediated kinase activation (microbial LPS and cytokines can activate kinases that phosphorylate tau) [140]