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This paper demonstrated that a small-molecule activator of glycolysis can limit inflammation through inhibition of the neutrophil oxidative burst

Currently, there is no cure for HSV-1 infections and those afflicted remain so for life

This gradual escalation prevents overwhelming side effects like flushing, nausea, or headaches that occur when starting at high doses, allows the pituitary to adapt to regular stimulation improving long-term response, and provides opportunity to identify minimal effective dose avoiding unnecessary higher dosing and associated costs