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Neurobescherming: Kan neuronen beschermen tegen schade bij neurodegeneratieve ziekten en beroertes

Li Y, Dang L, Lv C, Lin B, Tao J, Yu N, Deng Y, Wang H, Kang X, Qin H, Chen R, Li J, Liang Y, Liang Y, Shi Y (2024b) The safety of ixekizumab in Chinese adults with moderate-to-severe plaque psoriasis: analyses from a prospective, single-arm, multicenter, 12-week observational study

Compound 30 encompassing a homo tyrosine in a 14-membered macrocycle and with a trans double bond provided the lowest Ki value in the series, 1.8 nM, while the corresponding tyrosine analogues with the 13-membered ring system exhibited a Ki value of 50 nM

Some people may need weekly shots at first, then monthly for maintenance