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Furthermore, the relevance of this environment-diet-gene interaction to the patho-aetiology of contemporary disease needs to be explored with a considered approach, taking into account interactions between skin pigmentation, UVR exposure, folate status and folate-related gene epistasis

Instead of fitting into one receptor and flipping one switch, it influences the expression of roughly 4,000 human genes and acts as a copper delivery vehicle into cells, where copper helps drive enzymes involved in collagen synthesis, antioxidant defense, and tissue repair

10.1128/JB.00136-17 11 DasT.PainoD.ManoharanA.FarrellJ.WhiteleyG.KrielF