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In contrast, less severe mood disorders did not show this familial pattern, supporting the idea that BP-II is a distinct and genetically separate condition

Contributes to experimental cellular turnover modeling: By enabling removal of senescent cells, FOXO4-DRI supports investigation into how cellular turnover influences tissue equilibrium

Discussion With life expectancy projected to increase in the foreseeable future (Vaupel, 2010) it is important to develop strategies to extend and restore healthspan

N Engl J Med 350(23):23352342 Kabbinavar FF et al (2005) Combined analysis of efficacy: the addition of bevacizumab to fluorouracil/leucovorin improves survival for patients with metastatic colorectal cancer