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assessed the effect of adding synergists to resistant tick populations and found that there was a significant positive relationship between the resistance factor and the synergy factor with PBO and VER, suggesting that cytochrome P450 is involved in ivermectin resistance (Shakya et al

References J Glutathione

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It is a vital water-soluble antioxidant that helps neutralize free radicals, which can cause cellular oxidative stress and premature aging