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Acknowledgements This work was supported by the National Natural Science Foundation of China (82360716, 82070422, and 82200330), China Postdoctoral Science Foundation (2023T160526 and 2022M722571), Research Plan Project of Shaanxi Institute of Basic Science (22JHQ053), High-end Foreign Expert Introduction Program of National Science and Technology (G2022040014L), Qinchuangyuan Traditional Chinese Medicine Innovation Research and Development Transformation Project (2022-QCYZH-036)

Examples of research applications include: Receptor interaction research Peptide signalling pathway investigation Intracellular signalling modelling Comparative peptide studies Molecular pathway analysis Controlled in vitro research Laboratory signalling studies Grail Formula Quality Every Grail Formula research compound is produced under strict quality control procedures designed to support reliable laboratory experimentation

Copper Tripeptide-1 is the INCI (International Nomenclature of Cosmetic Ingredients) name for GHK-Cu