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The more severe diclofenac plus L-NAME- induced lesions were abrogated by L-arginine (to the diclofenac control level, diclofenac plus L-NAME plus L-arginine-treated rats) (but not below the control values, which was achieved with BPC 157(diclofenac plus L-NAME plus BPC 157-treated rats)) rather than the regular diclo- fenac lesions (mediated by COX inhibition and effects of diclofenac) which remained unopposed

Fermentable carbohydrate restriction reduces luminal bifidobacteria and gastrointestinal symptoms in patients with irritable bowel syndrome