Urrutia S, Bose P, Alvarado Y, Borthakur G , Ravandi F, Daver N, Pemmaraju N, Jabbour E, Takahashi K, Kadia T, DiNardo C, Kornblau S, Kanagal-Shamanna R, Huang X, Bodden K, Kantarjian H, Garcia-Manero G
However, this list is yet to be finalized and until the FDA evaluates and publishes a final rule regarding a substances inclusion on the 503A bulks list, the FDA has stated that it does not intend to take enforcement action against state-licensed pharmacies, federal facilities, or licensed physicians who compound drugs using bulk substances provided the following circumstances are met: The bulk drug substance is listed in 503A Category 1 on the FDAs website
As a topical cosmetic ingredient, it is present in many over-the-counter products
it binds toxins, heavy metals, and metabolic waste in the liver so they can be flushed