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Kalkan et al

Conclusions The goal of this review was to highlight factors that influence postnatal bone elongation with respect to their effects on IGF-1 activity in the growth plate, and in particular, the current state of knowledge regarding effects of IGF-1 and environmental variables, such as temperature, on bone elongation in cartilaginous growth plates

Furthermore, BRC has been demonstrated to improve leptin and GLP-1 levels, suggesting that BRC may exert a wide action on glucose regulation also through the regulation of food intake and endocrine pancreatic secretion, respectively (84)

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