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With regard to the relationship between BDNF and depressive disorders, there is evidence that expression and activity of BDNF in the hippocampus are decreased in response to stress and increased by antidepressant treatment [40,41,42,43]

The folded complexes (or MHC monomers) were concentrated, dialyzed and biotinylated in a solution containing D-biotin and ATP to which the BirA enzyme (Avidity) was added

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