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From 1,309 bioactive molecules screened, the computer analysis selected GHK at 1 micromolar and securinine at 18 micromolar as the optimal agents capable of reversing expression of 54 gene sets overexpressed in malignant invasive colon cancer

Plasma preparation We separated the resulting plasma into four preparation conditions that differed in anticoagulant used during sample collection, storage temperature, and time to deproteinization

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The mechanisms of NPTAs in AD treatment include the following four key aspects: Initially, the localized thermal effects during PTT improve the permeability of the BBB, facilitating drug transport across the BBB and enhancing drug accumulation in brain lesions