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Glutathione injections is widely used medically in patients with liver disease and data studying these patients revealed good safety profile

3.1 Mitochondria-derived peptides Mitochondria-derived peptides (MDPs), also known as mitochondrial microproteins, are encoded by short open reading frames (ORFs) located in mitochondrial DNA (mtDNA) (e.g., Merry et al., 2020

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Hepato-protectant (NAC) and ER stress inhibitor (4-PBA) significantly downregulated ER stress markers in the liver compared to the MTX group, as depicted in Figures 6AE