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doi: 10.1177/1534735420967084

Better animal models are needed in order to recapitulate human disease, diverse antigenic history (mixed infection and vaccination) and immune phenomena such as original antigenic sin and imprinting

For patients with type 2 diabetes and biopsy-proven NASH with fibrosis, pioglitazone may be considered under specialist supervision, as its use for liver disease is outside its licensed indication (type 2 diabetes) and requires careful assessment of potential risks and contraindications