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B Vitamins and the Brain: Mechanisms, Dose and Efficacy - A Review

The NICE Clinical Knowledge Summary on B12 and folate deficiency recommends assessing the underlying cause before choosing a treatment path, which is why speaking to a pharmacist or GP first matters

The 2024 NICE Guideline NG239 from the United Kingdoms National Institute for Health and Care Excellence similarly distinguishes between patients who can be managed with oral therapy and those who require intramuscular treatment

The SELECT trial enrolled over 17,000 participants with established cardiovascular disease and obesity (without diabetes) and followed them for a median of approximately 40 months