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GHK-Cu stimulates synthesis of type I collagen (structural support), type III collagen (tissue flexibility and repair), glycosaminoglycans, chondroitin sulfate, dermatan sulfate, and the small proteoglycan decorin

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Skin tissue particularly keratinocytes, melanocytes, and dermal immune cells expresses MC1R, and NF-B dysregulation underlies a range of inflammatory skin conditions