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Subsequently, NP4-Cy7.5 was intravenously injected into BALB/c mice, and the biodistribution of nanoparticles in mice was observed using an in vivo imaging system (IVIS)

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229,230 The leading response of astrocytes to infectious agents is reactive astrogliosis, which erects parenchymal barriers and encapsulates brain abscesses, thus preventing infection spread