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A recent meta-analysis of 12 observational studies found that higher dietary intake of vitamin B 12 was associated with a 23% lower risk of depression compared to lower intakes, but stratifying the data revealed a significant protective association in females, not in males (99)
In head and neck squamous cell carcinoma (HNSCC), increased histone lactylation, particularly at H3K9la, is associated with poor immunotherapy response
The Potential Molecular and Cellular Mechanism of Flavonoids for Iron Overload Based on the previous research results, we summarized the underlying mechanisms of flavonoids for treating iron overload according to the following three mechanisms: amelioration of iron status by various proteins and pathways, chelation of iron to reduce iron deposition, and resistance to oxidation to reduce iron overload-induced oxidative damage (Figure 3A)
In Arabidopsis , this functional redundancy appears at first glance to be circumscribed to the cytosol as organellar gr2 null mutants are lethal early in embryo development [124]
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