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You need layered clothing for the extreme cold: Thermal base layer (top and bottom) Fleece or down vest/jacket Waterproof and windproof jacket Trekking pants Gloves, wool hat, and scarf/neck gaiter Trekking boots with good grip Also bring sandals to use at the campsites

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It enhances key immune responses, including natural killer cell cytotoxicity, neutrophil phagocytosis, and monocyte activity (Simpson et al., 2015) while also promoting immunosurveillance (Lee et al., 2019), decreasing the number of senescent cells (Spielmann et al., 2011), and suppressing signaling pathways that promote stem cell exhaustion (Liu et al., 2023)