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Bastos MAV Jr, Oliveira Bastos PRH, Portella RB, Soares LFG, Conde RB, Rodrigues PMF Jr, et al

Metabolic pathways: B12 is a cofactor in two critical reactions: Methylmalonyl-CoA mutase: Converts methylmalonyl CoA (from odd-chain fatty acids and some amino acids) into succinyl-CoA, which enters the Krebs (TCA) cycle to make ATP (cellular energy)

Medicines Some medicines can interfere with thyroid hormone production and lead to hypothyroidism, including certain heart medicines bipolar disorder medicines cancer medicines Several recently developed cancer medicines, in particular, can either affect the thyroid directly or affect it indirectly by damaging the pituitary gland

Raw bean protein hydrolysates, at a concentration of 0.1 mg protein/mL, demonstrated notable potential by inhibiting lipid accumulation (27.9%) in the 3T3L1 cell line (FloresMedelln et al., 2021)