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In another study of schizophrenic patients (N=84), Berk et al 16 undertook a randomized, double-blind, placebo-controlled trial and found that NAC, administered at 1g twice daily for 24 weeks, was a moderately effective augmentation strategy and resulted in improvement in the study scales assessing positive and negative symptoms as well as overall functioning

These conformational changes lead to the swing of F272 6.44 and the pronounced outward displacement of the cytoplasmic end of TM6 (Fig

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Cancer Res 2004