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Figure 6B is reproduced from (Pu, C., 2024) under the CC BY-NC-ND license

The absorbance at 546 nm is measured in a Shimadzu UVPC 2100 spectrophotometer (A 546 16 = mg Hb/mL) against a blank containing water instead of hemolysate

This finding highlights not only the key role that mitochondrial metabolism has in modulating response and resistance to TS inhibitors, but the wider opportunity afforded to enhance TS inhibitor-mediated anti-cancer effects by targeting mitochondrial metabolism using metformin or other compounds with similar mitochondrial impact

By the end of the drip, the headache, nausea, and fog are usually gone or much better