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However it is with the balance between the oxidant and antioxidant species that the organism, will be able to obtain the conditions to a better performance of its functions, considering that a disturbance in this balance can result in a range of pathological processes (Bast et al, 1991)

Nevertheless, data on the natural history of disease can also be drawn from patients in clinical trials which are not engaged in treatment [175, 246]

(6) Michael Hjby Rasmussen, Obesity, growth hormone and weight loss, Molecular and Cellular Endocrinology, Volume 316, Issue 2, 2010, Pages 147-153

Ethics Statement The studies involving human participants were reviewed and approved by the IEC/IRB of North Rhine Medical Council (IRB number: 2018188)