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In case blood samples were further processed for a scRNA-seq, a density gradient centrifugation was then conducted using Histopaque 1077/1119 (Sigma-Aldrich) following the manufacturers protocol

6.1 Postbiotics Postbiotics are bioactive metabolites and cellular components produced by probiotics during fermentation or after cell lysis, representing a microbiome-based intervention that extends beyond live bacteria

A: Safety and effectiveness of Vesoret Tablet in infants below the age of one year have not been established

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